COBO Technologies - European CRISPR QC Company
COBO Technologies is an early-stage CRO company based in Copenhagen, Denmark, that is specialised in products and services for Quality Control of CRISPR cells.
Their proprietary CRISPR InDel Profiling Platform - CIPP, for detailed DNA mutation analysis ,was launched in December 2017 and in January 2019 the company launched, PIPPR, for extensive protein/proteome expression profiling using labelfree SWATH LC-MS.
With more than 50 global clients since the start in 2017, COBO Technologies is today one of the leading niche CRO´s within the CRISPR QC field.
COBO is also involved in development of new standards and guidelines for future safe CRISPR Medicine via it engagement in both the NIST Genome Editing Consortium (US) and CRISPOTs (EU).
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CRISPR QC Services and Products
CRISPR - gRNA Validation
Javier, CSO/Co-founder - ZeClinics, Spain
Application(s) of interest: gRNA validation and INDEL profiling of pools/clones
Application - other: Zebrafish genetic modification
In what field are you working? Biomedicine/Drug discovery/Human genetics
Why did you choose to use the CRISPR INDEL Profiling Platform (CIPP™) from COBO? We found the INDEL Profiling Platform appealing for analysing CRISPR mutagenesis efficiency in pools and individual zebrafish
Did this service solve your problem? Indeed
What did you particularly like about this service? It is fast, informative and reliable
Would you use this service again in the future for a new project? We are using the INDEL Profiling Platform (IDAA) extensively in several projects and we will continue doing so
Would you recommend this service to others in your network? We have already done so and we will keep doing it
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Katherine, VP, Research - NERx Biosciences, US:
Application(s): INDEL profiling of pools/clones, NHEJ/HDR inhibitor screening/validation
In what field are you working? Genome engineering applications
What was the "problem" you needed to solve? Testing NHEJ inhibitors
Why did you choose to use the CRISPR INDEL Profiling Platform (CIPP™) from COBO? Highly quantitative, minimal amount of material required, detailed profiling of In/dels, easy to interpret the results, highly accessible and excellent customer service, and reasonable prices.
Did this service solve your problem? Yes
What did you particularly like about this service? Highly quantitative
Would you use this service again in the future for a new project? Absolutely, we are already planning our next project.
Would you recommend this service to others in your network? yes
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Malene, PhD, Senior Research Scientist - Lundbeck Pharma, Denmark:
In what field are you working? Neuroscience
What was the "problem" you needed to solve? To understand how much INDEL formation our gRNAs were giving us in HEK cells
Why did you choose to use the CRISPR INDEL Profiling Platform (CIPP™) from COBO? Because it seemed like a very easy and informative technique/service not available from other places
Did this service solve your problem? Absolutely
What did you particularly like about this service? The information that the INDEL Profiling Service provided (precise and reproducible quantitation of INDEL formation), the good interaction with COBO Technologies and the nice software (ProfileIt) they developed.
Would you use this service again in the future for a new project? Yes, for sure
Would you recommend this service to others in your network? Absolutely